期刊名称：International Journal of Advanced Computer Science and Applications(IJACSA)
印刷版ISSN：2158-107X
电子版ISSN：2156-5570
出版年度：2019
卷号：10
期号：8
页码：1-5
出版社：Science and Information Society (SAI)
摘要：Different from cryptography which encodes data
into an incomprehensible format difficult to decrypt,
steganography hides the trace of data and therefore minimizes
attention to the hidden data. To hide data, a carrier body must be
utilized. In addition to the traditional data carriers including
images, audios, and videos, DNA emerges as another promising
data carrier due to its high capacity and complexity. Currently,
DNA based steganography can be practiced with either biological
DNA substances or digital DNA sequences. In this article, we
present a digital DNA steganography approach that utilizes the
CRISPR-Cas9 off-target editing such that the secret message is
fragmented into multiple sgRNA homologous sequences in the
genome. Retrieval of the hidden message mimics the Cas9 offtarget
detection process which can be accelerated by computer
software. The feasibility of this approach is analyzed, and
practical concerns are discussed.
