期刊名称：Journal of Materials and Environmental Science
印刷版ISSN：2028-2508
出版年度：2018
卷号：9
期号：6
页码：1676-1682
DOI：10.26872/jmes.2018.9.6.187
出版社：University of Mohammed Premier Oujda
摘要：Posidonia oceanica L., one of nine Posidonia species belongs to family Posidoniaceae,is completely restricted to the White Mediterranean Sea. The chemical components ofthe aqueous methanol extracts of P. oceanica leaves and balls were analyzed using LCESI-MS technique for the detection and identification of its genuine constituents. Sixphenolic acids, six flavonoids, two chalcones, two hydroxyl benzenes, three fatty acidderivatives, one anthocyanin and one sterol were identified or tentatively characterized.Also, the cytotoxic activity of the two extracts were investigated against epidermalcarcinoma cell lines of larynx (Hep2), colon (HCT116), liver (HepG2) and breast(MCF7). The leaves extract exhibited obviously higher antiproliferative activity againstHepG2 cell line with IC50 17 μg/ml and a moderate activity against Hep2 and HCT116with IC50 28.3 and 27.8 (μg/ml), respectively while the balls extract showed moderateactivity against HepG2, MCF7 and HCT116 with IC50 24.3, 22.6 and 22.5 (μg/ml),respectively. The antiviral activity of the two extracts was also investigated againstH5N1 virus, the balls extract showed a moderate % inhibition (45%) and no activityobserved for the leaves extract. Furthermore, the chemosystematic significance wascharacterized to compare between P. oceanica and other seagrass species.
