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  • 标题:Guidance for Using Tafenoquine for Prevention and Antirelapse Therapy for Malaria — United States, 2019
  • 本地全文:下载
  • 作者:Julia C. Haston, ; Jimee Hwang, ; Kathrine R. Tan,
  • 期刊名称:Morbidity and Mortality Weekly Report
  • 出版年度:2019
  • 卷号:68
  • 期号:46
  • 页码:1062-1068
  • DOI:10.15585/mmwr.mm6846a4
  • 出版社:Centers for Disease Control and Prevention
  • 摘要:What is already known about this topic? Malaria can be prevented by taking antimalarials when traveling to an area with malaria. Treatment of malaria caused by Plasmodium vivax and Plasmodium ovale requires antirelapse therapy to kill the dormant liver-stage parasite. What is added by this report? Adults aged ≥18 years can take tafenoquine (Arakoda 100 mg tablets) to prevent malaria. Persons aged ≥16 years requiring antirelapse therapy for P. vivax or P. ovale can take tafenoquine (Krintafel 150 mg tablets). Before using tafenoquine, quantitative testing to rule out glucose-6-phosphate dehydrogenase deficiency is required. What are the implications for public health practice? Tafenoquine is another option for malaria chemoprophylaxis and for antirelapse therapy. The simplified dosing regimen has the potential to improve adherence.
  • 关键词:Tafenoquine Malaria Prevention; Tafenoquine Malaria Relapse; Malaria; MMWR; Morbidity & Mortality Weekly Report; Public Health
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