摘要:What is already known about this topic? Bacterial contamination of platelets is rare (approximately one in 5,000 platelet units) but poses serious risk to platelet transfusion recipients. What is added by this report? Sepsis resulting from bacterial contamination of platelets can occur even with implementation of bacterial mitigation strategies. Whole genome sequencing indicated a potential common source of bacterial contamination among four cases of septic transfusion reactions occurring in three states. What are the implications for public health practice? Clinicians need to monitor for sepsis after platelet transfusions even after implementation of bacterial mitigation strategies and immediately report adverse reactions to platelet suppliers and hemovigilance systems.
关键词:Sepsis And Bacterial Contamination of Platelets; Bacterial Contamination And Sepsis; Sepsis And Platelet Transfusion; Sepsis And Adverse Transfusion Reactions; Sepsis; Bacterial Diseases; Blood Safety; MMWR; Morbidity & Mortality Weekly Report