摘要:What is already known about this topic? Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that disproportionately affects women and minorities. The 5-year survival rate of patients with SLE has been improving. What is added by this report? Using improved methods by following SLE patients carefully defined in a population-based registry, standardized mortality ratios were two to three times higher in persons with SLE than in the general population. Compared with whites with SLE, cumulative SLE mortality was significantly higher among blacks, with deaths occurring sooner after diagnosis and at a mean age approximately 13 years younger. What are the implications for public health practice? Current CDC-supported efforts to encourage early detection, diagnosis, and treatment, and to enhance self-management skills might mitigate racial disparities and improve overall outcomes in SLE.
关键词:Systemic Lupus Erythematosus; Lupus And Racial Disparities; Lupus And Mortality; Lupus In Georgia; Georgia Lupus Registry; MMWR; Morbidity & Mortality Weekly Report