摘要:What is already known about this topic? Candidemia is typically considered a health care–associated infection, but injection drug use (IDU) has emerged as an increasingly common condition associated with candidemia. What is added by this report? Among 203 candidemia cases in the Denver metropolitan area during May 2017–September 2018, 23 (11%) occurred in 22 patients who had a recent history of IDU. Many had disseminated infections with end organ dysfunction, and onset occurred both inside and outside the hospital setting. Six of the patients were observed injecting or attempting to inject drugs while hospitalized. What are the implications for public health practice? Opportunities to intervene during health care encounters to decrease IDU and unsafe injection practices might prevent infections, including candidemia. Preventing candidemia among persons who inject drugs requires both community-based and health care–based interventions.