摘要：What is already known about this topic? Gastroschisis prevalence has increased worldwide. A previous U.S. report found that gastroschisis increased during 1995–2012, with the greatest increase among mothers aged <20 years. What is added by this report? During 2011–2015, gastroschisis prevalence was 4.5 per 10,000 live births, which was 10% higher than the prevalence during 2006–2010. An ecologic analysis found a higher prevalence of gastroschisis in areas where opioid prescriptions rates were high, supporting epidemiologic data suggesting an association between opioid use during pregnancy and gastroschisis. What are the implications for public health practice? Further public health research on gastroschisis is needed to gain insight into etiology, including the possible role of opioid exposure during pregnancy on birth defects.
关键词：Gastroschisis Trends; Gastroschisis And Opioid Prescription Rates; Gastroschisis And Mothers; Gastroschisis And Live Births; MMWR; Morbidity & Mortality Weekly Report
