出版社：Sociedad Española de Dietética y Ciencias de la Alimentación (SEDCA)
摘要：Background: The loss of lean mass in the oncological patient
produces serious consequences such as: the decrease in
the quality of life, in tolerance to treatments and increase in
social healthcare costs.
Objective: The aim of the present study was to establish
and develop a predictive analytics which assesses for the lean
mass loss experienced in oncologic patients under radiotherapy
treatment.
Methods: A prospective analysis has been undertaken,
taking a sample of 231 oncologic patients which have been
exposed to radiotherapy treatment.
Anthropometric measurements have been recorded via
TANITA TBF-300 instrument.
Backward method has been used to determine the equation
which develops from a complete regression model including
several independent variables.
Results: Only 197 patients that conformed the sample
were studied. The most representative variable that contributed
to the lean mass loss has been taken as a reference
variable. This is the chemotherapy treatment (p = 0.02, IC =
95%), and through statistical analysis, the following equation
has been obtained:% lean mass loss = -0.453 + 0.167 % initial
water content – 0.065 % lean mass + 0.246 % weight
loss (R2 = 0.264, F = 5.375, p < 0.01).
Conclusion: The equation obtained to predict the % lean
mass loss, at any point or stage during the treatment course,
is effective and reliable.
关键词：Lean mass loss; radiation oncology; malnutrition; cancer;
