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  • 标题:Morphological Analysis of Spherical Adsorptive Carbon Granules Using Three-Dimensional X-Ray Micro-computed Tomography
  • 本地全文:下载
  • 作者:Ken-ichi Izutsu ; Yasuhiro Abe ; Chikako Yomota
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:2020
  • 卷号:68
  • 期号:2
  • 页码:179-180
  • DOI:10.1248/cpb.c19-00732
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The purpose of this study was to clarify applicability of three-dimensional X-ray micro-computed tomography (3D X-ray micro-CT) to elucidate interior morphology of spherical adsorptive carbon fine granules. Scanning of small single spherical granule hold on the rotating sample stage provided the structural information without particular preparation ( e.g. , slicing) that can affect the definite morphology. The three model formulations with similar appearance showed different internal structure in the 3D images, including large hollow in one of them. Other formulations showed some small empty or higher density area in the filled granules, suggesting uneven distribution of carbon. The results indicated relevance of the X-ray micro-CT analysis on the physical characterization of the spherical adsorptive carbon granule formulations..
  • 关键词:X;ray micro;computed tomography;spherical carbon granule;morphology;formulation
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