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  • 标题:Serum carotenoids and macular pigment optical density in patients with intestinal resections and healthy subjects: an exploratory study
  • 本地全文:下载
  • 作者:Jane N. Eriksen ; August P. Prahm ; Mads Krüger Falk
  • 期刊名称:Journal of Nutritional Science
  • 印刷版ISSN:2048-6790
  • 电子版ISSN:2048-6790
  • 出版年度:2018
  • 卷号:7
  • 页码:1-4
  • DOI:10.1017/jns.2017.71
  • 出版社:Cambridge University Press
  • 摘要:Reduced absorption capacity in patients with intestinal resections (IR) could result in malabsorption of fat-soluble components like carotenoids, which are of clinical interest in relation to visual health. In this case cohort, we investigated the association between IR and serum lutein, zeaxanthin, β-carotene and macular pigment optical density, when compared with healthy controls. Ten patients with IR and twelve healthy controls were included in the study. Baseline characteristics were comparable between groups, except for higher serum TAG ( P 15 % lower in the patient group compared with healthy controls ( P < 0·05, adjusted for age) and, in the case of serum lutein and zeaxanthin, also for dietary intake of carotenoids. Results suggest that for a test of macular carotenoid supplementation, subjects with a potentially clinically significant carotenoid deficit could be recruited among patients with IR.
  • 关键词:Lutein;Zeaxanthin;Macular pigment optical density;Intestinal resection
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