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  • 标题:Bovine Paraoxonase-1 Activity in Oxidative Stress -
  • 本地全文:下载
  • 作者:Nabil M. Taha ; Abd El Wahab A. Mandour ; Mohamed A. Lebda
  • 期刊名称:Alexandria Journal of Veterinary Sciences
  • 印刷版ISSN:1110-2047
  • 电子版ISSN:1110-2047
  • 出版年度:2016
  • 卷号:51
  • 期号:2
  • 页码:233-238
  • DOI:10.5455/ajvs.229270
  • 出版社:International Medical Journal Management and Indexing System
  • 摘要:Association of serum paraoxonase (PON) activity and oxidative stress in dairy cows as well as the relation between PON activity and HDL-c concentration were studied. A significantly lower PON and arylesterase (ARE) activities (P˂ 0.05) was found in cows with oxidative stress (parasitic and mastitic animals) compared to clinically healthy cows. Serum glutathione peroxidase (GPX) activity and malondialdehyde (MDA) level were also markedly reduced in cows with oxidative stress where as the serum HDL-c, LDL-c and cholesterol concentration showed significant reduction than the values in healthy cows. The results indicate a higher serum TAG and vLDL-c values in normal cows than in oxidative stress cases. The total protein content, albumin and globulin concentrations were showed slightly lower values in oxidative stress than in normal cows. A decrease serum PON activity may lead to reduction of anti oxidative protection during marked oxidative stress.
  • 关键词:Bovine paraoxonase; Oxidative stress; Glutathione peroxidase; Malondialdehide
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