摘要:Introduction Academic follow-up (cohorts) of medical students during training is a source of relevant information. Objectives To identify academic performance and graduation rates indicators, and their relationship with gender in 25 cohorts of medical students at UNAM Faculty of Medicine in Mexico City. Methods Longitudinal design of true cohorts, with analysis of the academic records of 24,529 students (classes of 1986 to 2010). Results In recent years, more women than men study medicine, and students are younger and have higher high school and college grades. During the first year of medical school, grades are low and only half of the student population complete all mandatory courses without failing. Graduation rates after 5 years are 40% and after 8 years 75%. Conclusions Gender and academic outcomes are related. It is important to develop early interventions to improve the educational process.