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  • 标题:Nutritional approach as therapeutic manipulation in inflammatory bowel disease
  • 本地全文:下载
  • 作者:Jin Young Yoon
  • 期刊名称:Intestinal Research
  • 印刷版ISSN:1598-9100
  • 电子版ISSN:2288-1956
  • 出版年度:2019
  • 卷号:17
  • 期号:4
  • 页码:463-475
  • DOI:10.5217/ir.2019.00078
  • 出版社:Korean Association for the Study of Intestinal Diseases
  • 摘要:Malnutrition is observed more frequently in patients with inflammatory bowel disease (IBD) than in the general population and associated with adverse clinical outcomes. This study aimed to review the current knowledge regarding the efficacy of dietary and nutritional intervention in IBD patients. Exclusive enteral nutrition might be inferior to corticosteroid treatment in adults with active Crohn’s disease (CD) but might even be superior considering the adverse effects of corticosteroid treatment in children. Total parenteral nutrition has no advantage over enteral nutrition, which is considered a more physiologic modality in organ function. Current guidelines do not yet recommend ω3-polyunsaturated fatty acid supplementation for the prevention and maintenance of remission in IBD patients. Dietary fiber supplementation could be effective in the relief of symptoms and maintenance of remission in ulcerative colitis (UC). Although vitamin D may be favorable to clinical course of IBD and bone density. Probiotic supplementation has proven to be effective in preventing and treating pouchitis for UC but is less effective in treating CD. Nutritional interventions not only correct nutritional deficiencies but also improve symptoms and clinical courses of the disease. Hence, nutritional approaches need to be developed to significantly evaluate the effectiveness of dietary interventions used to treat IBD.
  • 关键词:Nutrition; Crohn disease; Colitis; ulcerative; Inflammatory bowel disease
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