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  • 标题:Reflections on the origin of life: More than an 'evolutionary' problem
  • 本地全文:下载
  • 作者:Kepa Ruiz-Mirazo ; Alvaro Moreno
  • 期刊名称:Mètode Science Studies Journal - Annual Review
  • 印刷版ISSN:2174-9221
  • 出版年度:2016
  • 期号:6
  • DOI:10.7203/metode.6.4997
  • 出版社:http://www.uv.es
  • 摘要:This paper argues that the question of the origin of life cannot be explained by appealing exclusively to Darwinian evolutionary mechanisms, as many experts tend to assume, but requires a profound change in perspective.Accordingly, we highlight the fact that, in order to operate as a diversification force (and indirectly, a force for a potential increase in complexity), natural selection requires a number of conditions to be met in order for it to be possible: specifically, self-sustained and self-(re-)productive chemical organisation within a sufficiently large phenotypic space (that is, a wide range of functions).Therefore, we suggest an extension of the «self-organising» paradigm towards a «self-(re-)productive» one as an alternative to the main proposals regarding the origin of life, based on molecular populations (typically RNA) subject to Darwinian evolution.Such a paradigm would adequately portray the specificity of the biological phenomenon (particularly, its metabolic and cellular dimension) and would be relevant before, during, and after natural selection started to operate.
  • 其他摘要:This paper argues that the question of the origin of life cannot be explained by appealing exclusively to Darwinian evolutionary mechanisms, as many experts tend to assume, but requires a profound change in perspective. Accordingly, we highlight the fact that, in order to operate as a diversification force (and indirectly, a force for a potential increase in complexity), natural selection requires a number of conditions to be met in order for it to be possible: specifically, self-sustained and self-(re-)productive chemical organisation within a sufficiently large phenotypic space (that is, a wide range of functions). Therefore, we suggest an extension of the «self-organising» paradigm towards a «self-(re-)productive» one as an alternative to the main proposals regarding the origin of life, based on molecular populations (typically RNA) subject to Darwinian evolution. Such a paradigm would adequately portray the specificity of the biological phenomenon (particularly, its metabolic and cellular dimension) and would be relevant before, during, and after natural selection started to operate.
  • 关键词:origen de vida; metabolismo; complejidad; evolución abierta
  • 其他关键词:Self-organisation;protocells;metabolism;phenotypic/functional diversity;open evolution
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