期刊名称：Journal of Patient-Centered Research and Reviews
电子版ISSN：2330-0698
出版年度：2020
卷号：7
期号：2
页码：206-212
DOI：10.17294/2330-0698.1720
出版社：Aurora Health Care
摘要：This pilot study aimed to assess the feasibility of precisely measuring tumor diameter and myometrial
invasion in patients with endometrioid endometrial cancer (EEC) using preoperative contrastenhanced magnetic resonance imaging (MRI). Adult patients with confirmed diagnosis of complex
hyperplasia with atypia or EEC were included. Three radiologists separately measured tumor diameter
and myometrial invasion. Basic descriptive statistics were used to describe patient characteristics
and to compare radiology- and pathology-measured tumor diameter and myometrial invasion. Using
the pathology results for tumor diameter as the gold standard for comparison, at least 1 radiologist
was able to predict largest tumor diameter within 5 mm for 41.7% of patients. Similarly, based
on pathology results for myometrial invasion, at least 1 radiologist was able to predict myometrial
invasion within 5% for 50% of patients. All radiologists were able to predict superficial (<50%) or deep
(≥50%) myometrial invasion for 75% of patients, with greater sensitivity, specificity, and accuracy
for deep myometrial invasion. Given variation among radiologic measurements, it is difficult to
recommend preoperative MRI as a basis for measuring tumor diameter and myometrial invasion.
Even so, the ability to predict superficial versus deep myometrial invasion may benefit patients with
EEC for whom surgery is not a viable option or for those seeking fertility-sparing treatment options.
