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  • 标题:Asymptotic analysis of a vector-borne disease model with the age of infection
  • 本地全文:下载
  • 作者:Xia Wang ; Yuming Chen ; Maia Martcheva
  • 期刊名称:Journal of Biological Dynamics
  • 印刷版ISSN:1751-3758
  • 电子版ISSN:1751-3766
  • 出版年度:2020
  • 卷号:14
  • 期号:1
  • 页码:332-367
  • DOI:10.1080/17513758.2020.1745912
  • 出版社:Taylor & Francis
  • 摘要:Abstract Formulae display: ? Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. Vector-borne infectious diseases may involve both horizontal transmission between hosts and transmission from infected vectors to susceptible hosts. In this paper, we incorporate these two transmission modes into a vector-borne disease model that includes general nonlinear incidence rates and the age of infection for both hosts and vectors. We show the existence, uniqueness, nonnegativity, and boundedness of solutions for the model. We study the existence and local stability of steady states, which is shown to be determined by the basic reproduction number. By showing the existence of a global compact attractor and uniform persistence of the system, we establish the threshold dynamics using the Fluctuation Lemma and the approach of Lyapunov functionals. When the basic reproduction number is less than one, the disease-free steady state is globally asymptotically stable and otherwise the disease will be established when there is initial infection force for the hosts. We also study a model with the standard incidence rate and discuss the effect of different incidence rates on the disease dynamics.
  • 关键词:Vector-borne disease; age of infection; horizontal transmission; threshold dynamics; global stability
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