摘要:BACKGROUND: Despite efforts of scientists and clinicians evidences for the effectiveness of post-stroke rehabilitation programmes following BTX-A injection still look weak and unclear. OBJECTIVE: To evaluate the therapeutic effect of botulinum toxin A (BTX-A) injection on spastic upper limbs muscles. CASE STUDIES PRESENTATION: Six ambulatory post-stroke patients were recruited in this study. All parameters was measured twice: before the injection and after 4±1 weeks of treatment. The participants received the same number of therapeutic sessions (ambulatory physiotherapy: 5 days a week). A significant decrease in the AS/MAS and MRC scores observed after treatment showed improvement. CONCLUSIONS: Treatment with BTX-A, initially expensive, may be regarded as effective due to low incidence of side effects, short period of hospitalization (if necessary), and reduction in the use of other drugs/therapies.