摘要：The purpose of this study was to investigate the ejfects of L-carnitine on total antioxidative sta tus.Subjects were eight mod erately trained male volunteers.4.0 mM lactate thresholds were determined.A dose of 2 g.d'1 L-camitine (Sigma Tau,Pomezia) w as supplem ented for one wee k fo llow ing placebo administration at the same dose and duration.Threshold running fo r 20 min dec rea sed serum carnitine concentrations significa ntly (p<0∙05) before and after placebo,and after L-carnitine administration.L-carnitine supplementation increased serum free carnitine concentra tions significan tly at rest (p<0.05) and insign ifican tly afte r exercise (p=0.066),while placebo had no effect.Although mean values of total antioxid ative sta tus at rest were increase d both follow ing placebo (0.6 %) a nd L-camitine adm inistrations (2.4 %),post-exercise values were only incr eased after L-camitine administration (3.5 o∕o).However,none of these elevations wa s significan t (p>0.05).Plasma lactate concentrations were not affe cted both after placebo and L-camitine adm inistra tions.There were no correlations among se ru mfre e carnitine,total antioxida tive status a nd plasm a lactate concentrations.
