摘要：Tanıtım: Mandibula metastazları oldukça nadir görülür ve mandibula malignitelerinin yaklaşık %1’inden daha azını teşkil eder. Mandibulaya metastaz olan olgularda hastalar genellikle çenede şişlik, çene kemiği ile dişlerde ağrı, ve diş kaybı gibi şikayetlerle başvururlar. Metastatik lezyonların belirtilerinin periodontal hastalıklarla karışma olasılığı nedeniyle dikkatli olmak gerekir ve ayırıcı tanıda primer kemik tümörü olan osteosarkom, primer intraosseöz skuamöz karsinom, ameloblastoma, temporomandibuler eklem hastalıkları akılda tutulmalıdır. Tedavi seçenekleri cerrahi ve ilave kemoradyoterapi olmakla birlikte, prognoz kötüdür ve genellikle tedavi palyatif amaçlı yapılmaktadır. Olgu Bildirimi: Rektum adenokarsinomu nedeni ile 3 yıl önce opere olan 51 yaşında kadın hasta kliniğimize çenede şişlik şikayeti ile başvurdu. Hastanın kraniyal manyetik rezonans ve maksillofasiyal bilgisayarlı tomografi görüntüleri incelendiğinde sağ mandibula ramusunda, kondili de tutan kemikte yıkıma yol açan lezyon tanımlandı. Hastaya yapılan insizyonel biyopsi sonrasında histopatolojik tanı kolorektal adenokarsinom ile uyumlu olarak raporlandı. Hasta medikal onkoloji bölümüne yönlendirildi. Sonuç: Mandibula lezyonlarının ayırıcı tanısı çok dikkatli bir şekilde yapılmalı ve metastatik tümörlerin akılda tutulması gerekmektedir. Öyküsünde akciğer, meme, kolorektal kanser ve benzeri tümörü olan hastalarda baş boyun bölgesinde metastatik tümörlerin oluşabileceği düşünülmeli ve dişlerde ağrı, diş kaybı dikkate alınmalı, gerekli radyolojik incelemeler sonrası mutlaka biyopsi yapılmalıdır. Introduction: Mandibular metastases are quite rare and they constitute less than about %1 of the mandibular malignancies. In mandibular metastatic cases, patients’ complaints generally include bony swelling with pain, tooth pain and tooth loss. Mandibular metastatic lesions mimic periodontal diseases; therefore careful examination is necessary. In differential diagnosis, osteosarcoma, which is a primary bone tumor, primary intraosseous squamous carcinoma, ameloblastoma, and temporomandibular joint diseases should be taken into consideration. Treatment modalities are surgery and chemoradiotherapy. Because of the poor prognosis, the goal of the treatment is only palliative. Case Report: A 51-year-old woman, operated due to rectal adenocarcinoma 3 years previously, was referred to our clinic with a complaint of swelling on the jaw. Cranial magnetic resonance imaging and maxillofacial computed tomography revealed a mass that extended to condyle and lead to bone destruction on the right ramus of the mandible. An incisional biopsy was performed. The histopathology was consistent with colorectal adenocarcinoma metastasis. The patient was referred to a medical oncologist. Conclusion: Differential diagnosis of mandibular lesions should be made carefully, and metastatic tumors should be kept in mind. In patients with history of lung cancer, breast cancer, colorectal carcinoma or similar tumors, oral findings such as tooth pain and tooth loss should be taken into consideration, as these may be the signs of head and neck metastases. Biopsy must be performed after radiological examination.
其他摘要：Introduction: Mandibular metastases are quite rare and they constitute less than about %1 of the mandibular malignancies. In mandibular metastatic cases, patients’ complaints generally include bony swelling with pain, tooth pain and tooth loss. Mandibular metastatic lesions mimic periodontal diseases; therefore careful examination is necessary. In differential diagnosis, osteosarcoma, which is a primary bone tumor, primary intraosseous squamous carcinoma, ameloblastoma, and temporomandibular joint diseases should be taken into consideration. Treatment modalities are surgery and chemoradiotherapy. Because of the poor prognosis, the goal of the treatment is only palliative. Case Report: A 51-year-old woman, operated due to rectal adenocarcinoma 3 years previously, was referred to our clinic with a complaint of swelling on the jaw. Cranial magnetic resonance imaging and maxillofacial computed tomography revealed a mass that extended to condyle and lead to bone destruction on the right ramus of the mandible. An incisional biopsy was performed. The histopathology was consistent with colorectal adenocarcinoma metastasis. The patient was referred to a medical oncologist. Conclusion: Differential diagnosis of mandibular lesions should be made carefully, and metastatic tumors should be kept in mind. In patients with history of lung cancer, breast cancer, colorectal carcinoma or similar tumors, oral findings such as tooth pain and tooth loss should be taken into consideration, as these may be the signs of head and neck metastases. Biopsy must be performed after radiological examination.
关键词：Baş ve boyun kanseri ; kolorektal kanser ; mandibula ; metastaz
其他关键词：Colorectal cancer ; head and neck cancer ; mandible ; metastasis
