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  • 标题:Sugammadex-Associated Hypotension, Bradycardia, Asystole, and Death
  • 本地全文:下载
  • 作者:Kazim Mirza ; Kathryn Landoski ; Dilip Thakar
  • 期刊名称:Case Reports in Anesthesiology
  • 印刷版ISSN:2090-6382
  • 出版年度:2020
  • 卷号:2020
  • 页码:1-2
  • DOI:10.1155/2020/8767195
  • 出版社:Hindawi Publishing Corporation
  • 摘要:On December 16, 2015, the Food and Drug Administration (FDA) in the United States approved sugammadex (Bridion, Merck and Co), a modified gamma-cyclodextrin, to be used as a reversal agent. It is a first and unique selective nondepolarizing steroidal muscle relaxant (NDSMR) binding agent with a great affinity for rocuronium and vecuronium. However, there have been several recently published case reports of bradycardia and asystole immediately after sugammadex administration for the reversal. This report presents a case of sugammadex administration followed by rapidly progressing bradycardia leading to asystole and subsequent death. The family has provided the written consent to share this case report.
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