首页    期刊浏览 2024年11月27日 星期三
登录注册

文章基本信息

  • 标题:Synthesis of Nitriles via the Iodine-Mediated Dehydrosulfurization of Thioamides
  • 本地全文:下载
  • 作者:Yuki Murata ; Hitomi Iwasa ; Mio Matsumura
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:2020
  • 卷号:68
  • 期号:7
  • 页码:679-681
  • DOI:10.1248/cpb.c20-00228
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:A simple general method for the synthesis of nitriles using the inexpensive and easy to handle iodine (I2 ) is described herein. The reaction of thioamides with I2 in the presence of triethylamine at room temperature under aerobic conditions afforded various nitriles bearing aryl, vinyl, and alkyl groups in good-to-excellent yields. This method was also effective for conversion from thioureas to cyanamides.
  • 关键词:iodine;thioamide;nitrile;cyanamide;dehydrosulfurization
国家哲学社会科学文献中心版权所有