期刊名称：Pakistan Journal of Analytical & Environmental Chemistry
印刷版ISSN：1996-918X
电子版ISSN：2221-5255
出版年度：2005
卷号：6
期号：2
页码：80-83
语种：English
出版社：National Centre of Excellence in Analytical Chemsitry
摘要：Prevalent environmental toxicity of various chemical groups of pesticides and their effects leading towards increasing morbidity and mortality in the farmers is of great concerned. In this situation the biochemical biomarkers are regarded as meaningful tools for monitoring toxic end points. This work was aimed to assess the toxic impacts of carbamates through some biochemical parameters and useful validity of these biomarkers was also observed. Present results reveal inhibition of cholinesterase activity by 46%,whereas bilirubin,urea and creatinine levels in serum were increased and sugar values was decreased at highly significant level (p<0.001). Urine urobilinogen concentration found raised significantly at high level (p<0.001) while protein,urea,creatinine and sugar values in urine of the farmers seen non-significant. This study concluded that the selected biochemical parameters can be used as biomarkers to assess the significant toxic effects in the exposed populations..
关键词：Carbamates;Biochemical biomarkers;Farmers in Pakistan
