期刊名称：Pakistan Journal of Analytical & Environmental Chemistry
印刷版ISSN：1996-918X
电子版ISSN：2221-5255
出版年度：2008
卷号：9
期号：1
页码：1-6
语种：English
出版社：National Centre of Excellence in Analytical Chemsitry
摘要：Pesticides are major contaminating chemicals in agriculture environment and a hazard to exposed population. These compounds are absorbed by inhalation,ingestion,and dermal contact. Their bioavailability in the individuals can lead to a variety of metabolic and systemic dysfunctions,and even outright disease states. Therefore,the tremendous usage of pesticides has promoted toxicological studies in spraying community. This study comprising pesticide spray-workers (n=140) and controls (n=110) indicated highly significant effects by analytical means on serum cholinesterase level (p<0.001) through ANOVA. Duncan Multiple Range Test ranking for monocrotophos and carbaryl were similar though different than endosulfan and cypermethrin,which conceptualized the effects on cholinesterase level. The GC-MS detection of residue concentrations in blood serum samples of spray-workers;calculated for endosulfan,monocrotophos,carbaryl and cypermethrin were 0.009,0.005,0.05 and 0.08 mg/kg body weight respectively. It was further seen in light of reported NOAEL that indicated the effect and extent of exposure among the study population..
