期刊名称：Pakistan Journal of Analytical & Environmental Chemistry
印刷版ISSN：1996-918X
电子版ISSN：2221-5255
出版年度：2008
卷号：9
期号：1
页码：1-7
语种：English
出版社：National Centre of Excellence in Analytical Chemsitry
摘要：A new spectrophotometric method has been developed for the determination of the potent antibiotic ceftriaxone (CF) by derivatization with 4-dimethylaminobenzaldehyde (DAB). The derivative indicated molar absorptivity of 5.3 x 10 3 L mol -1 cm -1 at Îmax 397 nm and obeyed the Beerís law within 20-100 µgmL -1 . The color reaction was highly stable and did not show any change in absorbance up to 24 h. The method was successfully applied for the determination of CF from various pharmaceutical preparations available in local market. The amounts of CF found in various pharmaceutical preparations were within 237.4-990 mg ampoule -1 with standard deviation (SD) ± 0.0004-0.044 (n=3) respectively..
