摘要:Life currently offers various facilities. However,along with this there are many issues which trigger stress. In addition,there are many chemical elements and heavy metals which,when interacting can cause a variety of illnesses ranging from colds to cancer,including autism. This study aims to analyze the potential of the protein profile in the blood that cause autism based bioinformatics. Then,to inform the public,especially parents of autistic in Malang so as to provide insight into autism. This research could also be developed as the basis of laboratory research. The research is a qualitative descriptive,using three databases,namely the National Center for Biotechnology Information (NCBI),Uniprot,and the Protein Data Bank (PDB) and using software PyMOL. The results of this study show that: 1) protein in the blood that could potentially cause autism based on articles that mTOR,glutathione S transferase P,Chemokines monocyte chemotactic protein-1 (MCP-1),Interferon-∂-Inducible Protein-16 (IFI-16),and serotonin;2) The following proteins were analyzed using three databases (NCBI,Uniprot,and GDP) showed that the protein glutathione S transferase P is more potent against autism. This is because the protein's function is to prevent neurodegeneration;3) Research on the causes of autism is needed by parents of autistic children (society),so as to minimize access to the entry of such triggers..
其他摘要:Kehidupan saat ini menawarkan berbagai kemudahan. Namun,seiring dengan hal tersebut ada banyak permasalahan yang memicu stress. Selain itu,terdapat banyak unsur kimia dan logam berat yang jika saling berinteraksi dapat menimbulkan berbagai macam penyakit