摘要：Many researchers (e.g. Coffey et al., 2004) have indicated that recovery from acute exercise induced muscular fatigue could be expedited by increased rapidity of lactate (LA-) clearance from the blood. This argument is based on the following logical progression: Firstly, increased intra-myocellular LA- concentration has been proposed to exert various deleterious electrochemical influences over excitation/contraction coupling and metabolic function (e.g. Favero et al., 1997). Secondly, because LA- is extruded from the muscle cells to the blood in a concentration gradient dependent fashion (Mengual et al., 2003); lowered blood LA- concentration should therefore allow increased rapidity of myocellular LA- export. Finally, LA- accumulation is continually cited as having a causal relationship with exercise induced acidosis; and further that such acidosis is deleterious to muscular function (for review see Pedersen et al., 2004). Given that protons are co-transported out of the muscle cells with LA- at a 1:1 ratio (Mengual et al., 2003); it may appear this is another reason for suggesting increased LA- extrusion rate could be beneficial.
