出版社：National Research University Higher School of Economics (HSE)
摘要：This paper aims to estimate the cancer mortality and morbidity derivatives for the Russian population given the limited access to medical and demographic data. The multiple-decrement life table method - also known as the population model of cancer - was originally proposed by J. Duchêne and makes it possible to assess otherwise inaccessible indicators, such as the prevalence of cancer in the Russian population. Applying this model to the publicly available data on cancer mortality and morbidity, we were able to estimate the following indicators for the Russian population: average age at malignant neoplasms (MN) diagnosis, average duration of disease, prevalence of MN, and average age at death from MN. We aimed to determine whether the prevalence of MN is increasing in the Russian Federation and whether this growth is occurring due to expansion of morbidity. It was found that the average age at cancer diagnosis, along with the average age at death from cancer, is increasing in the Russian population, with the primacy of the latter. These processes are in turn resulting in an increase of the average number of years lived with cancer, hence justifying the claim for an expansion of morbidity. This phenomenon, along with the increase in the incidence of MN, is the cause of the increase in MN prevalence in Russia. Localizations with the highest and lowest MN prevalence were identified, as well as localizations for which the expansion of morbidity phenomenon does not occur. It was found that in Russia the general trend is for the expansion of morbidity, expressed in an increase of the number of years lived in an imperfect health condition. MN of the lip, oral cavity and esophagus (C00-C15) in women is the only localization for which this phenomenon is not observed. This localization is the only exception to the otherwise observed expansion of morbidity. The main limitations and drawbacks of the study are discussed in a separate section.
其他摘要：В данной работе предпринимается попытка оценки непубликуемых производных показателей онкологической заболеваемости и смертности в населении РФ с использованием таблиц множественного выбытия – популяционной модели рака Д. Дюшен в сложившихся условиях ог
关键词：multiple decrement life-tables; incidence and mortality of malignant neoplasms; prevalence of malignant neoplasms; derivatives of cancer mortality and incidence; oncological statistics; cancer data analysis
其他关键词：таблицы множественного выбытия; смертность и заболеваемость злокачественными новообразованиями; распространенность злокачественных новообразований; производные онкологической смертности и заболеваемости; анализ данных онкологической статистики
