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  • 标题:Effect of Vitamin A to reduce Parasitemia of Switzerland Strain Mice were infected by Plasmodium berghei
  • 其他标题:Pengaruh Pemberian Vitamin A terhadap Penurunan Parasitemia Mencit Strain Swiss yang diinfeksi Plasmodium berghei
  • 本地全文:下载
  • 作者:Umi Isnaeni, Retno Sri Iswari ; Umi Isnaeni, Retno Sri Iswari ; Nugrahaningsih WH
  • 期刊名称:Biosaintifika: Journal of Biology & Biology Education
  • 印刷版ISSN:2085-191X
  • 电子版ISSN:2338-7610
  • 出版年度:2012
  • 卷号:4
  • 期号:2
  • 页码:121-126
  • DOI:10.15294/biosaintifika.v4i2.3930
  • 语种:English
  • 出版社:Universitas Negeri Semarang
  • 摘要:Vitamin A is a vitamin that acts as an immunostimulant. This research aims to determine whether the administration of vitamin A can reduce parasitaemia of Plasmodium berghei in Switzerland strain mice. This research used 24 mice Switzerland strain mice 6-8 weeks old weighing 20-30 grams/tail. Research conducted experimentally by using time series design. In this research, the provision of vitamin A treatment with 3 doses of variation is 0 IU/g BW, 35 IU/g BW and 70 IU/g BW as well as the negative control group, with each group consisting of 6 mice. Vitamin A was given 1 hour before infection then treated mice to mice in the negative control group died. Thin blood smears were made 2 days and parasitaemia was calculated by Giemsa staining. Parasitaemia data were analyzed with ANOVA. Significant results then followed by a further test Post hoc at 1% error level. ANOVA test results for the treatment group B, C and D obtained value of p <0.001 for each treatment group. It is claimed that there are significant differences in the treatment given. Likewise for further Post hoc testing that has been done obtained value of p <0.001. It can be concluded that the administration of vitamin A affects the reduction in parasitaemia of Plasmodium berghei in Switzerland strain mice.
  • 其他摘要:Vitamin A merupakan vitamin yang berperan sebagai imunostimulan. Penelitian ini bertujuan untuk mengetahui apakah pemberian vitamin A dapat menurunkan parasitemia Plasmodium berghei pada mencit strain Swiss. Penelitian ini menggunakan 24 ekor mencit strai
  • 关键词:parasitemia; Plasmodium berghei; switzerland strain mice; vitamin A
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