摘要：This research aimed to find out the effectiveness of the implementation of problembased learning with Reguku on the topic of immune system for high school to students’ attitude of health caring and learning outcomes for high school student.This research uses preexperimental design approach which is helped with conducting one-group pretest-posttest design.There were four kinds of data analyzed in this research: (1) students’ score,(2) students’ attitude of health caring,(3) students’ response and (4) questionnaire of teacher’s response to problembased learning with Reguku.Students’ learning outcomes was analyzed using N-gain formula and classical completeness test,meanwhile the students’ attitude of health caring,students’ and teacher’s response to problem-based learning with Reguku were analyzed descriptively using percentage.The students’ attitude of health caring indicated a good condition which was 76,02%.The data of learning outcomes for student were obtained from the score of posttest,daily activity,discussion sheet,and exercise.Collectively,83,6% of the students from both classes passed the minimum passing score of classical completeness test and the increase of N-gain score is in medium criteria (0,345).Both the teachers and the students gave positive response on the implementation of problem-based learning with Reguku.Based on the research findings and discussion,it can be said that problem-based learning with Reguku is effective to be applied on the topic of immune system in SMA N 2 Bae Kudus.
