摘要：The role of cytochrome P450 in the metabolism of herbicides in plants is reviewed.Attention is especially focused on cytochrome P450 due to its role in herbicide metabolism in plants and selectivity for grown crops.The involvement of cytochromes in secondary metabolism in plants,and their roles in herbicide detoxification,demineralization,redox,dehydration,desulfurization and isomerization are explained.Examples are given that show the functioning of cytochrome P450 in biosynthetic processes,and its role in the metabolism of some herbicides in several cultivated and weed plant species.Great diversity of structure,functioning and number of cytochromes,accompanied by a considerable divergence of their respective genes,indicate the complexity of role and activity of cytochromes in metabolic processes of herbicides in plants.The fact that a large number of cytochrome P450 genes have been found in plants (510 genes classified into 52 families) is an additional indication of the intricacy of structure and functioning of cytochrome P450,its evolution and genetic regulation of its activity.
其他摘要：U ovom revijalnom radu razmatra se uloga citohroma P450 u metabolizmu herbicida u biljkama.Posebno se obrađuje značaj citohroma P450 za metabolizam herbicida u biljkama i selektivnost za gajene biljke.Pored uloge u sekundarnom metabolizmu u biljkama data je i njihova uloga u procesima detoksikacije herbicida,dimerizacije,redukcije,dehidratacije,desulfuracije i izomerizacije.Dati su brojni primeri funkcije citohroma P450 u biosintetičkim procesima,ali i primeri uloge citohroma P450 u metabolizmu pojedinih herbicida u nekim gajenim i korovskim biljkama.Velika raznovrsnost strukture,funkcije i broja citohroma,praćena velikom divergentnošću njihovih gena,ukazuje na svu složenost uloge i aktivnosti citohroma u procesima metabolizma herbicida u biljkama.Postojanje velikog broja citohrom P450 gena u biljkama (510 gena,razvrstanih u 52 familije) takođe ukazuje na složenost strukture i funkcije citohroma P450,evoluciju i genetsku regulaciju njihove aktivnosti.
关键词：Cytochrome P450;metabolism of herbicides;herbicides;resistence;secondary metabolism
