期刊名称：Ovidius University Annals, Series Physical Education and Sport/Science, Movement and Health
印刷版ISSN：1224-7359
出版年度：2010
卷号：10
期号：1
页码：29-36
语种：English
出版社：Ovidius University Press
摘要：Melatonin has a lipophilic property and is produced in a variety of organs including the pineal gland.It possesses several physiological properties that may play an important role in physiology and pathophysiology.Eight groups (E 10°C,E 23°C and E 37°C chronic treadmill exercise groups;ME 10°C,ME 23°C and ME 37°C melatonin chronic treadmill exercise groups;S 23°C and MS 23°C sedentary and melatonin-sedentary groups respectively) were formed and a total of 48 Sprague Dawley male rats,weighing 250-300 g were used in this study.In the study,the groups which took melatonin were given the related substance 5 mg/kg per day before the exercise for 4 weeks by intraperitoneally (I.P.) way.At the end of the training period (4 week) the rats were killed.Blood samples were collected for antioxidant and lipid peroxidation levels determinations.In the statistical analyses Anova,Duncan and t- test were used.MDA,GR levels are higher than those of ME23°C groups.GR level is higher in E10°C group compared to ME 10°C group.Serum MDA levels of the E 37°C group are lower than those of ME37°C group.Serum SOD levels are the same in E 23°C and E 37°C groups,SOD levels of both of then are lower than those of the E 10°C group.SOD levels in the sedentary and the other melatonin-sedentary group were significantly different.It was found out in the study that oxidative stress appeared most in cold environment,melatonin did not prevent oxidative stress in cold and hot environment but it activated antioxidant system and decreased emergence of free radicals at normal temperatures.
