期刊名称：Ovidius University Annals, Series Physical Education and Sport/Science, Movement and Health
印刷版ISSN：1224-7359
出版年度：2011
卷号：11
期号：1
页码：38-39
语种：English
出版社：Ovidius University Press
摘要：Many evidences show that physical activity increases oxygen consumption by 10- to 15-fold over common consumption and it resulting on produces an "oxidative stress" with excessive generation of free radicals and lipid peroxidation. On the other side,a defense system of free radical scavengers minimizes these dangerous radicals. One of the main antioxidative enzyme is superoxide dismutase (SOD),enzyme involve in decomposing superoxide radicals to hydrogen peroxide and play a significant role against oxidant stress,especially in the state of hypoxia,as a consequence of intense exercise. The effects of acute exercise on SOD activity and malondialdehyde (MDA - marker of lipid peroxidation),were determinate in plasma of athletes and compared with non-athletes (healthy volunteers). Activity of SOD was measured by commercial UV spectrophotometry test,while MDA was measured by Andreeva spectrophotometry method. Acute exercise showed effect on increased concentration of MDA after exercise in both investigated groups (p < 0.001),but with higher increase in non-athletes. Simultaneously,we noted statistical negligible differences in SOD activity before and after exercise,but we noted the greater base level of SOD activity in athletes vs. non-athletes (1356.5±456.8 U/gHb vs. 1189.7±358.7 U/gHb; p<0.05). The presence of high MDA level in athletes suggests an increased formation of free radicals in exercise. Increase of SOD activity is a consequence of subsequently compensated by an increase of antioxidants enzymes as a compensatory mechanism to prevent skeletal muscle damage because the enhanced production of superoxides and oxyradicals during exhaustive exercise.
