标题：COMPARATIVE EVALUATION OF REHABILITATION AND ACTOVEGIN TREATMENT VERSUS REHABILITATION TREATMENT IN PAINFUL DIABETIC NON INSULIN-DEPENDENT NEUROPATHY
期刊名称：Ovidius University Annals, Series Physical Education and Sport/Science, Movement and Health
印刷版ISSN：1224-7359
出版年度：2016
卷号：16
期号：2
页码：387-391
语种：English
出版社：Ovidius University Press
摘要：Aim: To compare the efficacy of Actovegin combined with rehabilitation versus rehabilitation in painful diabetic neuropathy (PDN).Methods: In this observational trial,28 patients received actovegin orally (divided in four groups,each group has 7 patients),first group rehabilitation without actovegin,second received 3 tablets of actovegin (1 tablet morning,1 tablet afternoon and 1 tablet evening) combined with rehabilitation,third group 6 tablets of actovegin (2 tablet morning,2 tablet afternoon and 2 tablet evening) combined with rehabilitation,fourth group 9 tablets of actovegin (3 tablet morning,3 tablet afternoon and 3 tablet evening) combined with rehabilitation.Results: The study was conducted between January 2015 and June 2015 and shows the results of drug therapy versus rehabilitation for painful diabetic non insulin-dependent neuropathy after 6 months.Actovegin combined with rehabilitation are compared with rehabilitation for their efficiency and also the global perception of change by the patients.Patients were not allowed any other pain medication.Conclusions: The study shows how the combination between actovegin and rehabilitation procedure are more efficiency than the rehabilitation alone,that suggest a neuroprotective activity of the drug.
