摘要：5-Methyl-6-phenyl-2-thioxothieno[2,3-d]pyrimidone derivative (2) reacted with hydrazonoyl chloride derivatives to afford triazolothienopyrimidones 4a–f.Also,acetone- -1-(2-amino-5-isopropyl-thiophene-3-carbonitrile) (3) reacted with functional and bifunctional groups to yield the corresponding compounds 5–11.The new products showed anti-inflammatory,analgesic,and ulcerogenic activities comparable to that of indomethacin and acetylsalicylic acid,respectively.
