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  • 标题:Chemical composition of endemic Centaurea austro-anatolica and studies of its antimicrobial activity against multi-resistant bacteria
  • 本地全文:下载
  • 作者:AYSEL UGUR ; NURDAN SARAC ; OZGUR CEYLAN
  • 期刊名称:Acta Pharmaceutica
  • 电子版ISSN:1846-9558
  • 出版年度:2009
  • 卷号:59
  • 期号:4
  • 页码:463-472
  • DOI:10.2478/v10007-009-0036-5
  • 语种:English
  • 出版社:Sciendo
  • 摘要:Hexane,chloroform,ethyl acetate and ethanolic extracts of the aerial parts of Centaurea austro-anatolica Hub.-Mor.(Asteraceae) were evaluated against microorganisms,including multiresistant bacteria,using a paper disc diffusion method.The chloroform extract exhibited significant antibacterial activity toward all bacteria tested.The chemical composition of the chloroform extract was determined by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS).The major compounds of the extract were caryophyllene oxide (21.32 %),spathulenol (10.86 %),n-tricosanol (9.58 %) and geranyl isovalerate (8.71 %).
  • 关键词:Centaurea austro-anatolica (Asteraceae);chemical composition;antimicrobial activity
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