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  • 标题:Haemostatic activity of butanolic extracts of Lamium album and Lamium purpureum aerial parts
  • 本地全文:下载
  • 作者:CORINA BUBUEANU ; RASIT IUKSEL ; MINERVA PANTELI
  • 期刊名称:Acta Pharmaceutica
  • 电子版ISSN:1846-9558
  • 出版年度:2019
  • 卷号:69
  • 期号:3
  • 页码:443-449
  • DOI:10.2478/acph-2019-0026
  • 语种:English
  • 出版社:Sciendo
  • 摘要:Lamium album and Lamium purpureum are species belonging to the genus Lamium.Aerial parts of the two species and roots of Lamium album have applications in human and veterinary traditional medicine.Haemostatic properties of butanolic extracts of Lamium species were investigated by two experimental models in Wistar rats: haemostatic test by tail bleeding time determination and acenocoumarolcarrageenan test.Results of the haemostatic test by tail bleeding determination demonstrated haemostatic activity of both extracts.In the acenocoumarol-carrageenan test,only the Lamium album extract showed haemostatic activity,comparable to that of vitamin K.Based on the qualitative chemical data on iridoid glycosides (HPTLC),8-acetylshanzhiside methyl ester might be assumed to be responsible for haemostatic activity.Based on the acute toxicity test,none of the extracts showed toxicity.
  • 关键词:Lamium album;Lamium purpureum;aerial parts;butanolic extract;haemostatic activity;toxicity
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