摘要：In 2011,the US National Research Council initiated a holistic concept of precision medicine (PM),based on the assumption that an individual's variations in genomic and epigenomic determinants will enable personalization of appropriate prevention and treatment interventions.[1] This in contrast to the “one size fits all” strategy for the management of diseases which has got a laid down standard of care.[2] The concept supposedly can predict which treatment to initiate and at what point of time in the natural course of a disease focused on an individual [Figure 1].[3],[4] It has been gaining ground in the last decade,and its application is being discussed. Currently,the National Institute of Health (NIH) has initiated a project on PM where they plan to recruit a cohort of one million volunteer who will provide genetic data,biological samples,and other health information to generate a big data for precise and targeted diagnosis and treatment options for a variety of diseases.
