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  • 标题:Clinical and hematological features of dengue in children presenting at a zonal hospital in a dengue-naive area
  • 本地全文:下载
  • 作者:Ashok Bhandari ; Navneet Nath ; Amrit Kumar
  • 期刊名称:Journal of Marine Medical Society
  • 印刷版ISSN:0975-3605
  • 电子版ISSN:2589-1235
  • 出版年度:2013
  • 卷号:15
  • 期号:1
  • 页码:14-18
  • DOI:10.4103/0975-3605.203266
  • 语种:English
  • 出版社:Medknow Publications
  • 摘要:Background: Dengue infection is endemic in most regions of India and is a major cause of morbidity and mortality.There is paucity of data from the Armed Forces.This report on 52 children is from a Zonal Hospital in a dengue mative area.Methods: A prospective,observational study of clinical features and laboratory parameters in children up to 15 years with dengue infection confrmed by ELISA for NS 1 antigen.Results: Mean age was 9.9 years,male to female ratio 1.08:1.All 52 had Dengue Fever with no hemorrhagic manifestations and all recovered.Leading symptoms were nausea (53.85%),myalgia (51.92%) and vomiting (50%).Significant laboratory findings included leucopenia (<6000/cumm) in 90.38%,thrombocytopenia (<1.0000/cumm) in 23.08%;elevated aspartateaminotransferase in 45.45% and raised alanineaminotransferase in 36.36%.All abnormalities resolved spontaneously.Conclusion: Lack of serious manifestations of dengue,nausea as the leading symptom,marked leucopenia and relatively less thrombocytopenia and elev ation of liver enzy mes.are aspects of this study different from reports of other published studies and therefore need further research.Pooling and analyzing data from all Armed Forces hospitals and extension of advanced investigation facilitis to all hospitals would provide fresh insights to aid in better management of dengue infections in children.
  • 关键词:Dengue infction;Children;Leucopenia;Thrombocytopenia.
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