摘要：Hemostasis is a complex process requiring the delicately coordinated activation of platelets and plasma clotting factors to form a platelet-fibrin clot.It is a fundamental principle of good surgical practice.Hemostasis was first referenced in the battle of troy and has hence been developing along with the science of surgery.The various means to hemostasis in the operating theatre include :Mechanical methods,Thermal/energy based methods,Chemical methods- Topical & Pharmacological.Fibrin sealants,gelatin-based products,oxidized cllulose,and cllagen products are the major classes of topical hemostatic agents that have evolved over the last 100 years.
