标题：Araujo F M,Kondo R N,Minelli L,Pyoderma gangrenosum : Skin grafting and hyperbaric oxygen as adjuvants in the treatment of a deep and extensive ulcer. An Bras Dermatol 2013; 88 (6 suppl 1) : 176-8
摘要：This case report describes the delivery of hyperbaric oxygen therapy (HBOT) to a case of Pyoderma Gangrenosum (PG). PG is a rare noninfectious neutrophilic dermatosis resulting from an aberrant immune response to as yet unidentified factors. The etiology and pathophysiology of PG are still poorly understood,a universal treatment regimen remains to be found. The treatment of PG is a challenge. The authors present a case of pyoderma gangreosum treated succesfully with antibiotics,immunosuppressant with corticosteroids along with skin grafting and hyperbaric oxygen as adjuvants in the treatment of a deep and extensive ulcer.PG is an off label use of HBOT and not included as a UHMS (Undersea Hyperbaric Medical Society) indication. HBOT is . established and effective treatment for acceleration of healing process of skin lesions that resists conventional treatment,like venous and arterial ulcers,diabetic foot ulcers and pressure ulcers.
