摘要：Highly Active Anti- Retroviral Therapy (HAART) is a triple combination of ART drugs and is an effective tool to control disease progression in HTV disease.HAART is not started in all patients of HIV and indication to start HAA RT depends on clinical symptoms,CD4 cell count,HIV viral load.Advantages of HAART includes suppression of viremia and virus shedding in semen and vaginal secretions,increased CD4+ T cell count,reduced immune activation,restoration of lymph node arch itecture,clin ical improvement,prolonged survival,fewer opportunistic infections and HIV-assoclated malignancies.Problem with therapy are pill burden,non-availability of drugs,food and storage restrictions,drug- drug interactions,severe side-effects,reduction in quality oflife measures,emergence of multiple drug resistance mutations.
