摘要：Background : There ure only very few studies which compared 25 and 50 microgram of misoprostol in relation to neonatal outcome and Indian data in this context are lacking.Methods : This study was carried out as a single centre,prospective,observational study which consisted of 1 00 term pregnant women divided in two groups.Neonatal outcome was compared in relation to frequency of abnormal fetal heart rate tracings,meconium passage,1- or 5-minute Apgar scores < 7,neonatal resuscitations,or admissions to the neonatal intensive care unit Result : Meconium stained liquor was observed in 6% of cases in both groups.Apgar score at 1 min was <7 in 10% of cases in 25 mcg group against 6% in 50 mcg group.Requirement of neonatal resuscitation was observed in 10% of cases in each group.Fetal heart rate abnormality was observed in 22% of cases in 50 mcg group against 12% in 25 mcg group.Neonatal problems were detected in 14% and 12% of cases in 25 mcg and 50 mcg group respectively.Statistically these difference were not significant.Conclusion: There is no significant difference in neonatal outcome with 25 and 50 microgram of misoprostol used.for induction of delivery in term pregnancy.
关键词：Induction of labour;Misoprostol;Neonatal outcome.
