摘要:background One of the smoking risk factors influencing nicotine dependency may be human personality;however,few studies have examined the association between Akiskal’s affective temperaments and smoking in adults.Our study aims to evaluate the associations between nicotine dependence and affective temperaments using the TEMPS-A.participants and procedure The sample in this study consisted of 678 healthy Cau_casian adults aged from 17 to 69 years,including 134 self-declared nicotine-dependent subjects (89 females and 45 males) and 544 self-declared non-nicotine-dependent subjects (352 females and 192 males).The Polish version of the Temperament Evaluation of Memphis,Pisa,Paris and San Diego Autoquestionnaire (TEMPS-A) was used to assess affective temperaments (depressive,cyclothymic,hyperthymic,irritable and anxious).results Nicotine-dependent individuals scored higher on cyclo_thymic,irritable and anxious temperaments than non-nic?otine-dependents (no significant differences with regard to depressive and hyperthymic temperaments).Among the nicotine-dependent individuals,females scored higher on anxious temperaments than males (no differences with regard to the other affective temperaments),and among the non-nicotine-dependent individuals,females exhibited more depressive,cyclothymic and anxious temperaments than males,while males exhibited more hyperthymic tem_peraments than females.conclusions The results suggest that affective,cyclothymic and irrita?ble temperaments in both genders and anxious temper?aments in females may be predictors of nicotine depen?dence in adults.