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  • 标题:Moringa oleifera Lam.ameliorates the muscles function recovery following an induced insult to the Sciatic nerve in a mouse model
  • 本地全文:下载
  • 作者:Aroona Razzaq ; Shoaib Ahmad Malik ; Farhan Saeed
  • 期刊名称:Food Science & Nutrition
  • 电子版ISSN:2048-7177
  • 出版年度:2020
  • 卷号:8
  • 期号:8
  • 页码:4009-4016
  • DOI:10.1002/fsn3.1620
  • 出版社:John Wiley & Sons, Ltd.
  • 摘要:Peripheral nerve injury (PNI) is an incapacitating situation and has no effective therapy until now. We examined the possible role of crude leaves of Moringa oleifera Lam. at 200 mg/kg body weight in accelerating the functional regain in the sciatic nerve lesion induced mouse model (Adult male albino mice (BALB/c). Motor functions were evaluated by using the sciatic functional index, muscle mass, and muscle grip strength measurement, whereas the sensory functions were evaluated by using the hot plate test. Blood glucose levels and blood cell composition were also analyzed. We found that the Moringa oleifera crude leaves endorse the sensory and motor functions reclamation following the PNI with a statistically significant difference ( p < .05). It also revitalizes the gastrocnemius muscle by mass restoration with glycemic management perspective. Conclusively, the crude powder of Moringa oleifera leaves exhibited a function restoration boosting property and further detailed studies for its application as a therapeutic agent are strongly recommended.
  • 关键词:blood glucose;Moringa oleifera;motor and sensory functional recovery;peripheral nerve injury;phytochemicals
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