摘要：The increasing of antimicrobial resistance in medical field has become a serious problem which is have to be solved by exploring raw material on natural product. Seaweed or macroalgae is one of marine natural wealth of Indonesia’s sea. In this research, lipid extraction of seaweed (macroalgae) Ulva fasciata has been done according to Folch method by using sochlet and mixure of solvent namely chloroform:methanol (2:1/ (v/v)). The result gave two phase namely chloroform phase (0,6% (v/b)) and methanol phase (7,79% (v/b)). Furthermore, both of phase of crude extract lipid Ulva fasciata were tested their antibacterial activities against Bacillus cereus bacterial which is three times. Tetracyclin is used as positive control and the solvent (methanol-chloroform) is used as negative control. The results were both of phase gave antibacterial activity namely 0,02 mm/ μg extract for chloroform phase and 0,02 mm/ μg extract for methanol phase.
