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  • 标题:Current Summary of Lymphocyte Survival Study
  • 本地全文:下载
  • 作者:NORI NAKAMURA ; MITOSHI AKIYAMA ; SEISHI KYOIZUMI
  • 期刊名称:Journal of Radiation Research
  • 印刷版ISSN:0449-3060
  • 电子版ISSN:1349-9157
  • 出版年度:1991
  • 卷号:32
  • 期号:SUPPLEMENT
  • 页码:327-329
  • DOI:10.1269/jrr.32.SUPPLEMENT_327
  • 摘要:A recently developed dose-survival assay in vitro using human G 0 T-lymphocytes from peripheral blood was employed to assess possible interindividual variation of cellular radiosensitivity. Currently lymphocytes from a total of 99 atomic bomb survivors were tested and D 10 , the X-ray dose required to kill 90% of the cells, was calculated for each test. The mean ± SD of D 10 value was 3.35 ± 0.22 Gy for 61 survivors whose DS86 dose is below 0.004 Gy and for 38 survivors of DS86 dose above 1.5 Gy it was 3.31 ± 0.26 Gy. So far, the results do not show any evidence in support of the hypothesis of a selective elimination of a radiosensitive subcohort among the survivors exposed to high doses.
  • 关键词:Dose survival; Lymphocyte; Colony assay; D 10
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