摘要：The reactions between tocopherol monoglucoside (TMG), a water-soluble vitamin-E derivative, with Br 2 · - , N 3 ·, (SCN) 2 · - , NO 2 ·, OH· and various halogenated peroxyl radicals were examined using a pulse radiolysis technique. The results demonstrate that TMG forms a stable phenoxyl radical at pH > 6.8. The thus-formed phenoxyl radical shows pH-dependent decay kinetics and is disproportionated by 2nd order kinetics at pH 2.3. It was observed that the TMG reactivity towards a halogenated peroxyl radical increases with the number of halogen atoms at the carbon atom having a peroxyl group. The reaction between the TMG phenoxyl radical and ascorbic acid was also examined using a pulse radiolysis technique. The results indicate that the TMG phenoxyl radical is repaired by ascorbate. Kinetic studies indicate that TMG may act as an antioxidant to repair free-radical damage to some biologically important compounds. The one-electron reduction potential for TMG was found to be 0.522 V ± 0.06 vs. NHE.
关键词：Pulse radiolysis; Electron transfer; Reduction potential; Free radical; Tocopherol monoglucoside
