摘要:The biological effects of low-dose radiation are not only of social concern but also of scientific interest. The radioadaptive response, which is defined as an increased radioresistance by prior exposure to low-dose radiation, has been extensively studied both in vitro and in vivo . Here we briefly review the radioadaptive response with respect to mutagenesis, survival rate, and carcinogenesis in vivo , and introduce our recent findings of cross adaptation in mouse thymic cells, that is, the suppressive effect of repeated low-dose radiation on mutation induction by the alkylating agent N -ethyl- N -nitrosourea. Translated and modified from Radiat. Biol. Res. Comm. Vol.43(4); 436-442, (2008, in Japanese).
关键词:Low-dose radiation; Mutagenesis; Threshold; N -ethyl;N -nitrosourea