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  • 标题:Whole-body retention and fetal uptake of 65Zn in pregnant mice fed a Zn-deficient diet.
  • 本地全文:下载
  • 作者:NAONORI MATSUSAKA ; HIDEKI SAKAMOTO ; ITARU SATO
  • 期刊名称:Journal of Radiation Research
  • 印刷版ISSN:0449-3060
  • 电子版ISSN:1349-9157
  • 出版年度:1995
  • 卷号:36
  • 期号:3
  • 页码:196-202
  • DOI:10.1269/jrr.36.196
  • 摘要:Whole-body retention and fetal uptake of 65 Zn under a Zn-deficient diet were studied in pregnant mice in the late gestational stage after a single oral administration of 65 Zn. Whole-body retentions were much greater in mice given a Zn-deficient diet than in those given a Zn-normal diet. Accordingly, the amount of 65 Zn transmitted to the offspring in utero was greater in the Zn-deficient diet group. In another experiment, fetal uptake of 65 Zn in dams on gestation day 17 was examined over a period of 24 hr after a single intravenous administration of 65 Zn to the Zn-deficient and Zn-normal animals. There was no major difference in fetal uptake between the two groups, indicative that approximately a similar proportion of the 65 Zn retained in the maternal body was transmitted to the in utero offspring in both groups.
  • 关键词:65 Zn; Retention; Fetal uptake; Zn deficiency
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