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  • 标题:Oral L-Carnitine used to treat narcoleptic type 1 patient during pregnancy - A case report
  • 本地全文:下载
  • 作者:Felipe Barros ; Ana Carolina Rodrigues Aguilar ; Sergio Tufik
  • 期刊名称:Sleep Science
  • 印刷版ISSN:1984-0659
  • 电子版ISSN:1984-0063
  • 出版年度:2018
  • 卷号:11
  • 期号:4
  • 页码:215-216
  • DOI:10.5935/1984-0063.20180035
  • 出版社:Brazilian Association of Sleep and Latin American Federation of Sleep Societies
  • 摘要:Narcolepsy type 1 is a sleep disorder characterized by excessive daytime sleepiness (EDS), sleep fragmentation, hypnagogic hallucinations, sleep paralysis, and cataplexy. Stimulant medications such as modafinil and amphetamines are the first-line medications for treating sleepiness. However, the management of narcolepsy during special circumstances of life such as pregnancy is complex. MMDM is a 34-year-old female with Narcolepsy type 1 treated with modafinil (400mg/d) and citalopram (20mg/d). Before she become pregnant, modafinil and citalopram were replaced for L-Carnitine 510mg/d with good outcome. She underwent an usual pregnancy and was submitted to a term cesarean delivery without child-birth complications. This is the first description of oral L-Carnitine such an alternative to treatment narcolepsy type 1 during pregnancy. Treat these patients is not easy but care narcolepsy pregnant is a challenging even bigger. In a disease without many treatment options, L-Carnitine can be used to treat daytime sleepiness during pregnancy in narcolepsy.
  • 关键词:L-Carnitine;Narcolepsy;Pregnancy
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